Regeneration for Scalp and Hair: The Science Behind Plinest® and Purasomes
Hair health is one of the clearest reflections of cellular balance. Stress, hormonal fluctuations, and environmental exposure can all affect scalp integrity, leading to thinning, dullness, and reduced density. Regenerative medicine offers a new, evidence-based approach – one that restores the scalp’s biological function and strengthens hair from within. Two advanced solutions within the DermaFocus portfolio – Plinest® Hair and Purasomes HSC50+ Hair & Scalp Complex – are redefining how practitioners approach hair restoration.
Understanding the Regenerative Approach to Hair Restoration
Traditional treatments tend to focus on stimulating follicles or concealing loss. Regenerative therapies address the underlying cause: cellular decline and inflammation within the scalp. By improving dermal structure, restoring hydration, and enhancing tissue communication, these treatments create the conditions for stronger, healthier hair growth over time.
Plinest® Hair: Revitalising the Scalp Through Polynucleotides HPT®
Plinest® Hair, powered by Polynucleotides HPT®, supports scalp renewal, follicular function, and dermal balance through advanced cellular regeneration. It activates fibroblasts, improves microcirculation, and restores structure within the extracellular matrix – essential for healthy hair anchoring and growth.
Clinical research has shown that treatment with Plinest® Hair can:
- Improve hair thickness by 18% after a full treatment course
- Increase scalp hydration by 28%
- Reduce hair loss by up to 38% within eight weeks
- Enhance overall hair strength and shine through improved scalp oxygenation and reduced oxidative stress
Plinest® Hair is suitable for both men and women and can be used to support general thinning, post-partum changes, or seasonal shedding. It delivers natural results by improving the biological function of the scalp, without altering hormone levels or blocking enzymatic activity.
Purasomes HSC50+: Advanced Regeneration with Exosome Technology
Purasomes HSC50+ Hair & Scalp Complex combines exosomes, growth factors, and bioactive molecules to restore scalp vitality and promote hair growth.
Based on Dermoaroma’s patented Amplex+ technology, Purasomes HSC50+ has been clinically shown to:
- Increase the proliferation index by 177% within 48 hours
- Boost IGF-1 production by 115% in 24 hours
- Increase miRNA-31 expression by 500%
- Reduce scalp redness by 36% and transepidermal water loss (TEWL) by 25% after four weeks
Together, these effects improve follicle health, enhance scalp hydration, and encourage stronger, denser hair growth.
Combination and Maintenance Protocols
Plinest® Hair and Purasomes HSC50+ can be used independently or combined for synergistic results. A typical protocol involves a course of three to five sessions, spaced three to four weeks apart.
Practitioners may begin with Plinest® Hair to optimise scalp structure and hydration, followed by Purasomes HSC50+ to enhance follicular activity through exosome-based regeneration. Both can be delivered via microneedling for improved precision and absorption.
Maintenance treatments every four to six months help sustain results and support long-term scalp health.
Training and Support Through RISE
Hair restoration demands an understanding of scalp anatomy, regenerative science, and patient management. Through RISE (Regenerative Innovation and Scientific Education), DermaFocus provides in-depth practitioner training, ensuring each treatment is delivered with precision, safety, and clinical confidence.
A Regenerative Future for Hair Health
Hair thinning and scalp ageing affect confidence and wellbeing as much as appearance. By integrating Plinest® Hair and Purasomes HSC50+ into practice, practitioners can deliver results that focus on tissue restoration, biological balance, and lasting improvement – moving beyond surface correction towards genuine regeneration.
Click here to learn more about Plinest® Hair, Purasomes HSC50+, and the educational opportunities available through RISE.






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