Revitalising the Perioral Area: A Regenerative Approach with Newest®
The perioral area, surrounding the lips and mouth, is one of the most expressive and dynamic parts of the face. It’s also among the first to show signs of ageing. Fine lines, dehydration, loss of elasticity, and skin crepiness can appear early due to repetitive movement, sun exposure, and a natural decline in collagen and elastin. Treating this delicate region requires precision, sensitivity, and products that respect both form and function. Newest®, a hybrid formulation combining Polynucleotides HPT® and Hyaluronic Acid, offers a regenerative approach that restores skin health while preserving natural expression.
The Challenge of the Perioral Region
Unlike the mid-face or cheeks, the skin around the mouth is thin, mobile, and subject to constant mechanical stress. Repetitive motion – speaking, eating, smiling – accelerates collagen breakdown and contributes to ‘barcode’ lines and dehydration. Traditional filler techniques can sometimes overcorrect or restrict movement, leading practitioners to seek alternatives that improve quality rather than volume.
The Newest® Solution
Newest® brings together two proven bioactive components for comprehensive skin renewal. Polynucleotides HPT® support fibroblast activation, collagen and elastin production, and tissue repair, while Hyaluronic Acid delivers immediate hydration and smoothness. Together, they work synergistically to improve elasticity, resilience, and radiance.
Clinical studies show measurable improvements with Polynucleotides HPT® formulations, including:
- 23% increase in elasticity
- 14% improvement in hydration
- 34% increase in brightness and radiance
- Reduction in fine lines and texture irregularities within weeks
For the perioral area, this translates into smoother, firmer, and more hydrated skin that retains natural movement and expression.
How to Integrate Newest® into Perioral Treatment Plans
Newest® can be used independently or as part of a wider regenerative protocol. Practitioners may:
- Deliver a course of three to four sessions spaced three to four weeks apart to restore hydration and elasticity.
- Use following energy-based or resurfacing treatments to accelerate healing and improve texture.
- Combine with other treatments to maximise results.
This structured approach allows practitioners to enhance perioral skin quality without adding bulk – achieving natural softness and long-term improvement.
A Natural, Confident Result
Effective perioral rejuvenation relies on improving skin quality and resilience rather than masking the signs of ageing. By strengthening dermal structure and restoring hydration, Newest® helps reduce fine lines and improve elasticity while maintaining full, natural movement. The result is visibly healthier, more balanced skin that reflects genuine regeneration rather than correction.
Education and Protocol Support
DermaFocus provides comprehensive training on regenerative techniques for complex areas such as the perioral region through RISE (Regenerative Innovation and Scientific Education). Practitioners gain access to detailed protocols, anatomical guidance, and expert-led workshops to ensure every treatment is safe, effective, and confidence-driven.
Newest® represents the evolution of perioral treatment – moving from volume correction to true tissue restoration.
Click here to learn more about Newest® and upcoming RISE training opportunities with DermaFocus.
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